If you’re living with knee osteoarthritis in London, Arthrosamid may be the treatment you’ve been waiting for. Available at Krida Harley Street, this innovative 2.5% polyacrylamide hydrogel injection offers a new approach to managing knee pain — without surgery and without repeated courses of treatment.

What Is Arthrosamid?

Arthrosamid is an intra-articular hydrogel injection developed by Contura International. Unlike hyaluronic acid (viscosupplement) injections, Arthrosamid is not biodegradable — it integrates with the synovial membrane of the knee, providing durable cushioning and reducing friction within the joint. Clinical trials, including the landmark HYDRA study, have demonstrated significant improvements in pain scores and physical function lasting up to two years from a single injection.

Why Choose Krida Harley Street for Arthrosamid?

At Krida, all Arthrosamid injections are performed under direct ultrasound guidance by consultant-level musculoskeletal specialists. Ultrasound imaging ensures the hydrogel is delivered precisely into the intra-articular space — maximising efficacy and minimising the small risk of peri-articular placement. We operate from our state-of-the-art clinic at 82 Harley Street, W1G, offering same-week appointments and a dedicated MSK multidisciplinary team.

Am I a Suitable Candidate?

Arthrosamid is generally indicated for patients with mild to moderate knee osteoarthritis (Kellgren-Lawrence grade 1–3) who have not achieved sufficient relief from physiotherapy, NSAIDs, or steroid injections. Our specialists will review your symptoms, imaging, and medical history to confirm suitability at your initial consultation.

What Does the Procedure Involve?

The injection is performed as a clinic procedure with no general anaesthetic required. Following skin preparation and local anaesthetic, the Arthrosamid hydrogel is injected under real-time ultrasound guidance. Most patients experience mild soreness for 24–48 hours, after which many report progressive improvement in pain and mobility over the following weeks.